We are Gecco Biotech B.V.

At Gecco Biotech, we are committed to devising and developing sustainable enzymatic solutions for a wide range of fields, including chemistry, pharma and F&F. Our extensive knowledge and in-house engineering pipeline ensures you receive a product tailored to your needs, quickly and reliably. Our services range from enzyme discovery & engineering to downstream processing. 

Using state of the art expertise, we are able to develop novel enzymes, or improve variants, by improving target processes through engineering of enzymes for increased stability, specificity or activity. Our systemized workflow allows us to transform your concept into sustainable solutions. 

We have also built a unique, diverse portfolio of enzymes and cofactors which are readily available. 

Read more about Gecco

Our Collaborators for in silico Protein Engineering



What we can do for you

Our products


GECCO-enzymes and GECCO-cofactors are offered in a stable form (lyophilized)


GECCO-enzymes and GECCO-cofactors are offered as purified products


GECCO-enzymes and GECCO-cofactors are provided ready-to-use


GECCO offers a unique collection of cofactors.

One type of cofactors offered by GECCO are the deazaflavin cofactors.

The natural deazaflavin cofactors, F420 an FO, are notoriously difficult to produce and isolate and are currently only commercially available at GECCO Biotech.

GECCO also offers other flavin cofactor analogs and various enzymes that can be used for cofactor recycling which include:

  • a thermostable NADPH oxidase for recycling NADP+
  • a thermostable flavin reductase for recycling reduced FAD or FMN
  • a glucose-6-phosphate dehydrogenase to recycle F420
  • a thermostable catalase to recycle hydrogen peroxide into dioxygen and water
  • various dehydrogenase that can recycle NADH or NADPH

Why work with us?

  • 1. Built on accumulated knowledge

  • 2. Extensive know-how in enzyme engineering

  • 3. Wide range of enzymes & cofactors already in portfolio

  • 4. Novel enzyme discovery on demand

  • 5. Enzyme engineering on demand

  • 6. Reliable support! Always ready to troubleshoot with you